Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management Alexza Pharmaceuticals.
Cassella continued, ‘In previous clinical research where we’ve dosed a lot more than 100 subjects, Staccato alprazolam demonstrated superb dose-proportionality, exhibited a median Tmax of 2 minutes, and was safe and well-tolerated.’.. Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management Alexza Pharmaceuticals, Inc. ARS takes place in a subset of patients with epilepsy who frequently experience breakthrough seizures, despite treatment with a normal regimen of anti-epileptic drugs.
Mice that did not receive genistein in utero had been much heavier as adults – dual the weight of their genistein-fed counterparts. Prenatal genistein also shifted the offspring’s coat color from yellow to brown, demonstrating a one nutrient can possess a widespread systemic effect, said the researchers. Genistein’s impact occurred early in pregnancy, the equivalent of eight gestational days in humans. The Duke scientists said their results lend support to the ‘developmental origins of adult disease’ hypothesis, in which an individual’s long-term wellness is normally influenced by prenatal elements. Results of the study, funded by the National Institute of Environmental Wellness Sciences and the National Cancer tumor Institute, are released in the journal Environmental Health Perspectives. (more…)